Product Description
VPS34 (phospho-Ser249) polyclonal antibody is available at gentaur for next week delivery
Background: ULK1 and ULK2 (for UNC-51-like kinase) encode similar amino-terminal serine/threonine kinase domains, a proline/serine-rich (PS) domain, and a species conserved carboxyl-terminal domain. Both share homology with the UNC-51 kinase from Caenorhabditis elegans and the APG1 kinase in yeast, which are involved in axonal extension and growth, and autophagy, respectively. ULK1 and ULK2 are thought to auto-phosphorylate the PS domain in vitro, and the significant homology among vertebrates suggest that ULK1 and ULK2 are involved in the regulation of fundamental biological processes.
Applications: WB
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ULK1 (S757) polyclonal antibody detects endogenous levels of ULK1 protein.
W4BiowMW: ~ 150 kDa
Reactivity: Human
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic peptide, corresponding to amino acids 700-800 of Human ULK1.Alternative Name:
Serine/threonine-protein kinase ULK1; Autophagy-related protein 1 homolog; ATG1; Unc-51-like kinase 1; ULK1; KIAA0722Western blot analysis: Western blot (WB) analysis of ULK1 (S757) polyclonal antibody at 1:500 dilution Lane1:L02 whole cell lysate(40ug) Lane2:Panc1 whole cell lysate(40ug) Lane3:C6 whole cell lysate(40ug) Lane4:AML-12 whole cell lysate(40ug)
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q8NEB9
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