UHRF1 polyclonal antibody (ChIP Grade)

Product Description

UHRF1 polyclonal antibody (ChIP Grade) is available at gentaur for next week delivery

Background: UHRF1, also named as ICBP90, NP95 and RNF106, is a putative E3 ubiquitin-protein ligase. It may participate in methylation-dependent transcriptional regulation. UHRF1 binds to inverted 5-CCAAT-3 box 2 in the TOP2A promoter, and activates TOP2A expression. It is important for G1/S transition and may be involved in DNA repair and chromosomal stability. UHRF1s ability to repress its direct target gene expression is dependent on PHD(UHRF1) binding to unmodified H3R2.

Applications:  WB IHC IF

Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability:  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity:  UHRF1 polyclonal antibody detects endogenous levels of UHRF1 protein.

W4BiowMW:  ~ 110 kDa

Reactivity: Human

Note:  For research use only, not for use in diagnostic procedure.

Immunogen:

Recombinant full length Human UHRF1.

Alternative Name:

E3 ubiquitin-protein ligase UHRF1; Nuclear protein 95; Nuclear zinc finger protein Np95; HuNp95; hNp95; RING finger protein 106; Transcription factor ICBP90; hUHRF1; ICBP90; NP95; RNF106

Western blot analysis:  Western blot analysis of UHRF1 polyclonal antibody

Immunohistochemistry:

Immunofluorescence analysis: Immunofluorescence analysis of U2OS cells, using UHRF1 polyclonal antibody

Host:  Rabbit

Swiss-Prot: Q96T88

 

 

 

 

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