Product Description
TYR polyclonal antibody is available at gentaur for next week delivery
Background: Tyrosinase (TYR), a type I membrane protein and copper-containing enzyme, is involved in the production of melanin, the primary pigment found in vertebrates. Melanin biogenesis requires the enzymatic activity of TYR, which catalyzes the critical and rate-limiting step of tyrosine hydroxylation in the biosynthesis of melanin. Defects effecting TYR activity result in various forms of albinism. The TYR-related proteins, TRP1 and TRP2, are also specifically expressed in melanocytes, and they likewise contribute to the synthesis of melanin within the melanosomes.
Applications: WB IHC IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: TYR polyclonal antibody detects endogenous levels of TYR protein.
W4BiowMW: ~ 80 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human TYR.Alternative Name:
Tyrosinase; LB24-AB; Monophenol monooxygenase; SK29-AB; Tumor rejection antigen AB; TYRWestern blot analysis: Western blot analysis of TYR antibody.
Immunohistochemistry: Immunohistochemistry (IHC) analysis of TYR polyclonal antibody in paraffin-embedded Human Stomach Cancer tissue.
Immunofluorescence analysis: Immunofluorescence analysis of MCF-7 cells, using TYR polyclonal antibody
Host: Rabbit
Swiss-Prot: P14679
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