Product Description
TXA synthase polyclonal antibody is available at gentaur for next week delivery
Background: TXA synthase, also referred to as thromboxane synthase or CYP5, is an enzyme that catalyzes the conversion of the prostaglandin endoperoxide (PGH2) into Thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. TXA synthase is an important part of the cytochrome P450 system. Thromboxane A2 plays a pivotal role in the maintenance of hemostasis and cardiovascular diseases along with Prostacyclin. The expression of TXA synthase has been found to be consistently upregulated in several types of cancer tissues suggesting the involvement of this enzyme in tumor growth in humans. Thromboxanes are produced by TXA synthase in excess in inflammatory bowel disease.
Applications: WB IHC IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: TXA synthase polyclonal antibody detects endogenous levels of TXA synthase protein.
W4BiowMW: ~ 50-56 kDa
Reactivity: Human,Mouse
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human TXA synthase.Alternative Name:
BDPLT14; CYP5; CYP5A1; Cytochrome P450 5A1; Cytochrome P450; family 5; subfamily A; polypeptide 1; FLJ52771; GHOSAL; Platelet cytochrome P450 subfamily V; TBXAS1; THAS; THAS_HUMAN; Thromboxane A synthase 1 (platelet); Thromboxane A synthase 1 (platelet; cytochrome P450; family 5; subfamily A); Thromboxane A synthase 1; Thromboxane A synthase 1 platelet cytochrome P450 subfamily V; Thromboxane-A synthase; TS; TXA synthase; TXAS; TXS;Western blot analysis: Western blot (WB) analysis of TXA synthase polyclonal antibody
Immunohistochemistry: Immunohistochemistry (IHC) analysis of TXA synthase polyclonal antibody in paraffin-embedded Human Thyroid Cancer tissue.
Immunofluorescence analysis: Immunofluorescence analysis of Hela cells, using TXA synthase polyclonal antibody
Host: Rabbit
Swiss-Prot: P24557
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