Product Description
TTLL12 polyclonal antibody is available at gentaur for next week delivery
Background: TTLL12 (tubulin tyrosine ligase-like family, member 12) is a 644 amino acid protein that contains one TTL domain. Of the fourteen members of the TTLL family that modify tubulin, TTLL12 is the least characterized member. TTLL12 is highly expressed in a multitude of metastatic prostate cancer cell lines, therefore, it is considered a target for tumor therapy. Overexpression of TTLL12 is suggested to alter chromosome ploidy, whereas downregulation of TTLL12 influence several post-translational modifications of tubulin.
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: TTLL12 polyclonal antibody detects endogenous levels of TTLL12 protein.
W4BiowMW: ~ 83 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant protein of human TTLL12.Alternative Name:
KIAA0153; Tubulin--tyrosine ligase-like protein 12Western blot analysis: Western blot analysis of extracts of various cell lines, using TTLL12 antibody.
Immunohistochemistry: Immunohistochemistry of paraffin-embedded human liver injury using TTLL12 antibody at dilution of 1:100 (x40 lens).
Immunofluorescence analysis: Immunohistochemistry of paraffin-embedded rat heart using TTLL12 antibody at dilution of 1:100 (x40 lens).
Host: Rabbit
Swiss-Prot: Q14166
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