TREM1 polyclonal antibody

Product Description

TREM1 polyclonal antibody is available at gentaur for next week delivery

Background: TREM-1 (triggering receptor expressed on myeloid cells-1) is expressed in monocytes and neutrophils but not in lymphocytes, dendritic cells, or other cell types. TREM-1 is a glycoprotein that is reduced by deglycosylation, in agreement with the predicted molecular mass. TREM-1 is an activating receptor of the Ig superfamily that is expressed on human myeloid cells, selectively expressed on blood neutrophils and a subset of monocytes, and is upregulated by bacterial LPS. Immunoblot analysis shows that TREM-1 is associated with DAP12, a molecule frequently associated with activating receptors. TREM-1 and the myeloid DAP12-associating lectin (MDL-1) are recently identified receptors which associate non-covalently with DAP12 to form receptor complexes that are involved in monocytic activation and inflammatory response.

Applications:  WB

Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability:  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity:  TREM1 polyclonal antibody detects endogenous levels of TREM1 protein.

W4BiowMW:  ~ 25kDa

Reactivity: Human

Note:  For research use only, not for use in diagnostic procedure.

Immunogen:

Synthetic peptide, corresponding to Human TREM1 .

Alternative Name:

Triggering receptor expressed on myeloid cells 1;TREM-1;Triggering receptor expressed on monocytes 1;CD354;TREM1

Western blot analysis:  Western blot (WB) analysis of TREM1 polyclonal antibody at 1:2000 dilution Lane1:The spleen tissue lysate of Rat(40ug) Lane2:The spleen tissue lysate of mouse(40ug) Lane3:HepG2 whole cell lysate(40ug) Lane4:A549 whole cell lysate(40ug) Lane5:THP-1 whole cell lysate(40ug) Lane6:PC12 whole cell lysate(40ug) Lane7:Raw264.7 whole cell lysate(40ug)

Immunohistochemistry:

Immunofluorescence analysis:

Host:  Rabbit

Swiss-Prot: Q9NP99

 

 

 

 

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