Product Description
TRAPPC10 polyclonal antibody is available at gentaur for next week delivery
Background: TRAPPC10, also known as TMEM1 (transmembrane protein 1), EHOC1 (epilepsy holoprosencephaly candidate 1 protein) or GT334, is a widely expressed 1,259 amino acid protein that may function in vesicular transport. Despite its name, TRAPPC10 does not contain transmembrane domains. It is the human ortholog of the yeast Trs130 protein and its structure and function appears to be conserved. Localizing to the cis-Golgi apparatus, TRAPPC10 is believed to be involved in transport from the endoplasmic reticulum (ER) to the Golgi functioning as a component of the multisubunit transport protein particle (TRAPP) complex. Mutations in the gene encoding TRAPPC10 may be involved in autoimmune polyglandular disease type 1 or Unverricht-Lundborg disease, an autosomal recessive type of progressive myoclonic epilepsy.
Applications: WB IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: TRAPPC10 polyclonal antibody detects endogenous levels of TRAPPC10 protein.
W4BiowMW: ~ 112 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human TRAPPC10.Alternative Name:
Trafficking protein particle complex subunit 10; Epilepsy holoprosencephaly candidate 1 protein; EHOC-1; Protein GT334; Trafficking protein particle complex subunit; TMEM1; Transport protein particle subunit TMEM1; TRAPP subunit TMEM1; TRAPPC10; EHOC1; TMEM1Western blot analysis: Western blot analysis of extracts of various cell lines, using TRAPPC10 antibody.
Immunohistochemistry: Immunofluorescence analysis of U2OS cells using TRAPPC10 antibody.
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P48553
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