Product Description
TMS1 polyclonal antibody is available at gentaur for next week delivery
Background: ASC (apoptosis-associated speck-like protein containing a CARD, also known as TMS1 or PYCARD) is a member of the CARD-containing adaptor protein family. ASC is a 195 amino acid protein that contains an N-terminal pyrin-like domain (PYD) and an 87 residue C-terminal CARD. This motif is characteristic of numerous proteins involved in apoptotic signaling. Fluorescence microscopy demonstrates a ring-like expression in some transfected cells. Immunofluorescence microscopy demonstrates that induction of apoptosis causes a CARD-dependent shift from diffuse cytoplasmic expression to punctate or spherical perinuclear aggregates.
Applications: WB IHC IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: TMS1 polyclonal antibody detects endogenous levels of TMS1 protein.
W4BiowMW: ~ 21 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human TMS1.Alternative Name:
Apoptosis-associated speck-like protein containing a CARD; hASC; Caspase recruitment domain-containing protein 5; PYD and CARD domain-containing protein; Target of methylation-induced silencing 1; PYCARD; ASC; CARD5; TMS1Western blot analysis: Western blot analysis of extracts of various cell lines, using PYCARD antibody at 1:1000 dilution.
Immunohistochemistry: Immunohistochemistry of paraffin-embedded rat kidney using PYCARD antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis: Immunohistochemistry of paraffin-embedded mouse liver using PYCARD antibody at dilution of 1:100 (40x lens).
Host: Rabbit
Swiss-Prot: Q9ULZ3
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