Product Description
TIMP3 polyclonal antibody is available at gentaur for next week delivery
Background: TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases 1, 2, 3 and 4) complex with metalloproteinases such as collagenases, gelatin-ases and stromelysins, resulting in irreversible inactivation of the metallopro-teinase. TIMP-1 has been found to be identical to EPA (erythroid-potentiation activity). Parathyroid hormone has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus and remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart, with low levels expressed in liver, brain, lung, thymus and spleen.
Applications: WB IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: TIMP3 polyclonal antibody detects endogenous levels of TIMP3 protein.
W4BiowMW: Refer to figures
Reactivity: Human,Mouse,Rat,Monkey
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human TIMP3.Alternative Name:
Metalloproteinase inhibitor 3; Protein MIG-5; MIG5; Tissue inhibitor of metalloproteinases 3; TIMP-3; TIMP3Western blot analysis: Immunofluorescence analysis of MCF-7 cells using TIMP3 antibody.
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P35625
"
