Product Description
TDRKH polyclonal antibody is available at gentaur for next week delivery
Background: TDRKH (tudor and KH domain-containing protein), also known as TDRD2 (tudor domain-containing protein 2), is a 561 amino acid protein that contains two KH domains and one tudor domain. TDRKH exists as two alternatively spliced isoforms and interacts with HIWI and HILI2. The gene that encodes TDRKH contains roughly 21,310 bases and maps to human chromosome 1q21. With roughly 3,000 genes that span about 260 million base pairs, chromosome 1 makes up approximately 8% of the human genome. There are also a large number of diseases associated with chromosome 1, notably, the rare aging disease Hutchinson-Gilford progeria which is associated with the LMNA gene that encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.
Applications: WB
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: TDRKH polyclonal antibody detects endogenous levels of TDRKH protein.
W4BiowMW: ~ 72 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human TDRKH.Alternative Name:
Tudor and KH domain-containing protein; Tudor domain-containing protein 2; TDRKH; TDRD2Western blot analysis: Western blot analysis of extracts of various cell lines, using TDRKH antibody.
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q9Y2W6
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