Product Description
STXBP1 polyclonal antibody is available at gentaur for next week delivery
Background: Munc18-1 belongs to the Munc18 protein family that also includes Munc18-2 and Munc18-3. These proteins are highly conserved at the amino acid sequence level and play a critical role in membrane fusion. Munc18 proteins control SNARE complex formation and interact with syntaxin. In Munc18-1 knockout mice, neurotransmitter release is completely abolished. In addition, Munc18-1 acts as a molecular chaperone for syntaxin-1, allowing for formation of the SNARE complex at the plasma membrane. Munc18-1 also acts as a regulator of vesicle docking during exocytosis.
Applications: WB
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: STXBP1 polyclonal antibody detects endogenous levels of STXBP1 protein.
W4BiowMW: ~ 70kDa
Reactivity: Human,Mouse,Rabbit
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic peptide, corresponding to Human STXBP1.Alternative Name:
Syntaxin-binding protein 1; MUNC18-1; N-Sec1; N-Sec1;Protein unc-18 homolog 1; Unc18-1; Protein unc-18 homolog A; Unc-18A; p67; STXBP1; UNC18AWestern blot analysis: Western blot (WB) analysis of STXBP1 polyclonal antibody at 1:500 dilution Lane1:U-87MG whole cell lysate(40ug) Lane2:C6 whole cell lysate(40ug) Lane3:SHSY5Y whole cell lysate(40ug) Lane4:K562 whole cell lysate(40ug) Lane5:RAW264.7 whole cell lysate(40ug) Lane6:The Brain tissue lysate of Mouse(40ug) Lane7:The Brain tissue lysate of Rat(40ug)
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P61764
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