Product Description
SQSTM1 / p62 polyclonal antibody is available at gentaur for next week delivery
Background: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: SQSTM1 / p62 polyclonal antibody detects endogenous levels of SQSTM1 / p62 protein.
W4BiowMW: ~ 62kDa
Reactivity: Human, Mouse, Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human SQSTM1 / p62Alternative Name:
SQSTM1;A170;DMRV;FTDALS3;NADGP;OSIL;PDB3;ZIP3;p60;p62;P62bWestern blot analysis: Immunoprecipitation analysis of 200ug extracts of HeLa cells, using 3 ug SQSTM1 / p62 antibody. Western blot was performed from the immunoprecipitate using SQSTM1 / p62 antibody at a dilition of 1:1000.
Immunohistochemistry: Western blot analysis of extracts of various cell lines, using SQSTM1 / p62 antibody at 1:1000 dilution.
Immunofluorescence analysis: Immunohistochemistry of paraffin-embedded rat kidney using SQSTM1 / p62 Antibody at dilution of 1:200 (40x lens).
Host: Rabbit
Swiss-Prot: Q13501
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