Product Description
SOCS3 polyclonal antibody is available at gentaur for next week delivery
Background: The SOCS (suppressor of cytokine signaling) gene family consists of a group of proteins that negatively regulate cytokine signal transduction. The SOCS family proteins contain a central SH2 domain and a carboxy-terminal region termed the “SOCS box.” The SOCS-1 (also called SSI-1 and JAB), SOCS-2 (also called SSI-2 and CIS2) and SOCS-3 (also called SSI-3 and CIS3) genes are known to be upregulated by IL-6 and other cytokines. SOCS-4, SOCS-5, SOCS-6 and SOCS-7 were identified by their sequence homology with the SOCS box. CIS (for cytokine-inducible SH2-containing protein) is also a member of the SOCS family.
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: SOCS3 polyclonal antibody detects endogenous levels of SOCS3 protein.
W4BiowMW: ~ 30 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human SOCS3.Alternative Name:
Suppressor of cytokine signaling 3; SOCS-3; Cytokine-inducible SH2 protein 3; CIS-3; STAT-induced STAT inhibitor 3; SSI-3; SOCS3; CIS3; SSI3Western blot analysis: Western blot analysis of extracts of mouse spleen, using SOCS3 antibody.
Immunohistochemistry: Immunohistochemistry of paraffin-embedded rat heart using SOCS3 antibody.
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: O14543
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