Product Description
SNW1 polyclonal antibody is available at gentaur for next week delivery
Background: This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants.
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: SNW1 polyclonal antibody detects endogenous levels of SNW1 protein.
W4BiowMW: Refer to Figures
Reactivity: Human,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant protein of human SNW1Alternative Name:
Bx42;FUN20;NCOA-62;Prp45;PRPF45;SKIIP;SKIP;SKIP1;Bx42;NCOA-62;Prp45;PRPF45;SKIIP;SKIPWestern blot analysis: Immunohistochemistry of paraffin-embedded rat liver using SNW1 antibody.
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q13573
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