SETD7 polyclonal antibody

Product Description

SETD7 polyclonal antibody is available at gentaur for next week delivery

Background: Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins.

Applications:  WB IF

Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability:  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity:  SETD7 polyclonal antibody detects endogenous levels of SETD7 protein.

W4BiowMW:  ~ 41 kDa

Reactivity: Human,Mouse,Rat

Note:  For research use only, not for use in diagnostic procedure.

Immunogen:

Alternative Name:

Western blot analysis:  Western blot analysis of extracts of various cell lines, using SETD7 antibody at 1:1000 dilution. Lysates/proteins: 40ug per lane. Exposure time: 30s.

Immunohistochemistry: Western blot analysis of extracts of various cell lines, using SETD7 antibody at 1:1000 dilution. Lysates/proteins: 40ug per lane. Exposure time: 30s.

Immunofluorescence analysis:

Host:  Rabbit