SENP6 (K1077) polyclonal antibody

Product Description

SENP6 (K1077) polyclonal antibody is available at gentaur for next week delivery

Background: SUMO (small ubiquitin-related modifier), a member of the ubiquitin-like protein family, regulates diverse cellular functions of a variety of target proteins including transcription, DNA repair, nucleocytoplasmic trafficking and chromosome segregation. SUMO precursor proteins undergo cleavage of the residues after the “GG” region by SUMO-specific proteases in maturation. This cleavage of the precursor is a prerequisite for subsequent sumoylation. The sentrin-specific (or SUMO-specific) protease (SENP) proteins belong to the peptidase C48 family and include SENP1-3 and SENP5-8. SENP1, SENP2 and SENP3 degrade UBL1 and SMT3H2 conjugates and subsequently release the monomers from sumoylated substrates.

Applications:  WB IHC

Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability:  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity:  SENP6 (K1077) polyclonal antibody detects endogenous levels of SENP6 protein.

W4BiowMW:  ~ 126 kDa

Reactivity: Human,Rat

Note:  For research use only, not for use in diagnostic procedure.

Immunogen:

Synthetic peptide, corresponding to amino acids 1040-1089 of Human SENP6.

Alternative Name:

Sentrin-specific protease 6; SUMO-1-specific protease 1; Sentrin/SUMO-specific protease SENP6; KIAA0797; SSP1; SUSP1; FKSG6

Western blot analysis:  Western blot (WB) analysis of SENP6 pAb at 1:1000 dilution Lane1:PC3 whole cell lysate(40ug) Lane2:CT-26 whole cell lysate(40ug)

Immunohistochemistry: Immunohistochemistry (IHC) analyzes of SENP6 (K1077) pAb in paraffin-embedded human lung carcinoma tissue.

Immunofluorescence analysis:

Host:  Rabbit

Swiss-Prot: Q9GZR1

 

 

 

 

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