Product Description
SAFB2 polyclonal antibody is available at gentaur for next week delivery
Background: SAF-B2 (scaffold attachment factor B2) is a nuclear matrix-associated protein that binds to matrix- or scaffold-associating regions (MARs or SARs) on DNA and interacts with RNA polymerase II and serine-/arginine-rich RNA processing factors (SR proteins). SAF-B2, and the related SAF-B, bind to the estrogen receptor (ER) and are expressed in several breast cancer cell lines at varying levels. Subsequently, SAF-B and SAF-B2 may play a role in breast cancer by mediating cellular proliferation and division. Unlike SAF-B, which is exclusively nuclear, SAF-B2 is found in the cytoplasm as well as the nucleus.
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: SAFB2 polyclonal antibody detects endogenous levels of SAFB2 protein.
W4BiowMW: ~ 160 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant protein of human SAFB2.Alternative Name:
Scaffold attachment factor B2; SAF-B2; SAFB2; KIAA0138Western blot analysis: Western blot analysis of extracts of various cell lines, using SAFB2 antibody.
Immunohistochemistry: Immunohistochemistry of paraffin-embedded human prostate using SAFB2 antibody at dilution of 1:100 (x40 lens).
Immunofluorescence analysis: Immunohistochemistry of paraffin-embedded rat brain using SAFB2 antibody at dilution of 1:100 (x40 lens).
Host: Rabbit
Swiss-Prot: Q14151
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