Product Description
RUVBL1 polyclonal antibody is available at gentaur for next week delivery
Background: Pontin 52 is nuclear matrix protein that is primarily expressed in the nucleus and is also present in the cytoplasm. Pontin 52 is expressed in the nucleoplasm of whole cells, but is not present in the nucleoli. Pontin 52 is also designated RUVBL1, for E. coli RuvB-like 1 protein, or NMP 238, and is the human homolog of rat TIP49. Pontin 52 contains an ATPase/helicase motif and may represent a class of cofactors recruited by transcriptional activation domains that function in diverse pathways. For instance, in vivo, Pontin 52 is complexed with Myc and Reptin 52, which is a Pontin 52 related protein also designated RUVBL2. The interaction of Pontin 52 with Myc is dependent upon a Myc domain essential for oncogenic activity, suggesting that functional Pontin 52 is an essential mediator of Myc oncogenic transformation. The gene encoding human Pontin 52 maps to chromosome 3q21.
Applications: WB IHC IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: RUVBL1 polyclonal antibody detects endogenous levels of RUVBL1 protein.
W4BiowMW: ~ 55 kDa
Reactivity: Human,Mouse
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human RUVBL1.Alternative Name:
49 kDa TATA box binding protein interacting protein; 49 kDa TATA box-binding protein-interacting protein; 49 kDa TBP interacting protein; 49 kDa TBP-interacting protein; 54 kDa erythrocyte cytosolic protein; ECP-54; ECP54; ERYTHROCYTE CYTOSOLIC PROTEIN, 54-KD; INO80 complex subunit H; NMP 238; Nuclear matrix protein 238; Pontin 52; PONTIN; RuvB like 1; RuvB-like 1; RUVB1_HUMAN; RUVBL1; RVB1; TAP54 alpha; TAP54-alpha; TIP49; TIP49a; TIP60 associated protein 54 alpha; TIP60-associated protein 54-alpha;Western blot analysis: WesternBlot (WB) analysis of RUVBL1 polyclonal antibody
Immunohistochemistry:
Immunofluorescence analysis: Immunofluorescence analysis of A549 cells, using RUVBL1 polyclonal antibody
Host: Rabbit
Swiss-Prot: Q9Y265
"
