Product Description
RPS27A polyclonal antibody is available at gentaur for next week delivery
Background: Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus. When expressed in yeast, the protein is post-translationally processed, generating free ubiquitin monomer and ribosomal protein S27a. Ribosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteins. It contains C4-type zinc finger domains and is located in the cytoplasm. Pseudogenes derived from this gene are present in the genome. As with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubi. Multiple alternatively spliced transcript variants that encode the same proteins have been identified.
Applications: WB IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: RPS27A polyclonal antibody detects endogenous levels of RPS27A protein.
W4BiowMW: ~ 14 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human RPS27A.Alternative Name:
Ubiquitin-40S ribosomal protein S27a; Ubiquitin carboxyl extension protein 80; Ubiquitin; 40S ribosomal protein S27a; RPS27A; UBA80; UBCEP1Western blot analysis: Western blot analysis of extracts of HL-60 cell lines, using RPS27A antibody.
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P62979
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