RGS14 polyclonal antibody

Product Description

RGS14 polyclonal antibody is available at gentaur for next week delivery

Background: RGS domains bind directly to activated Ga subunits and act as GTPase-activating proteins (GAPs) to attenuate and/or modulate hormone and neurotransmitter receptor-initiated signaling by both Ga-GTP and Gbg. RGS proteins shorten the lifetime of the activated G protein. Western blot analysis shows strong expression of RGS14 as a primarily cytosolic protein restricted to brain and spleen. It is suggested that RGS14 may constitute a bridging molecule that allows cross-regulation of signaling pathways downstream from G protein-coupled receptors.

Applications:  WB

Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability:  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity:  RGS14 polyclonal antibody detects endogenous levels of RGS14 protein.

W4BiowMW:  ~ 54 kDa

Reactivity: Human,Mouse

Note:  For research use only, not for use in diagnostic procedure.

Immunogen:

Alternative Name:

Western blot analysis:  Western blot analysis of extracts of various cells, using RGS14 antibody.

Immunohistochemistry:

Immunofluorescence analysis:

Host:  Rabbit