Product Description
Rad50 polyclonal antibody is available at gentaur for next week delivery
Background: Rad52 family members (Rad50, Rad51B/C/D, Rad52, Rad54, MRE11) mediate DNA double-strand break repair (DSBR) for DNA damage that otherwise could cause cell death, mutation or neoplastic transformation. Rad51 (RECA, BRCC5) interacts with BRCA1 and BRCA2 to influence subcellular localization and cellular response to DNA damage. BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis from deregulation of Rad51. Rad52 forms a heptameric ring that binds single-stranded DNA ends and catalyzes DNA-DNA interaction necessary for the annealing of complementary strands.
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Rad50 polyclonal antibody detects endogenous levels of Rad50 protein.
W4BiowMW: ~ 180 kDa
Reactivity: Human,Mouse
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human Rad50.Alternative Name:
DNA repair protein RAD50; hRAD50; RAD50Western blot analysis: Western blot analysis of Rad50 polyclonal antibody
Immunohistochemistry: Immunohistochemistry (IHC) analysis of Rad50 polyclonal antibody in paraffin-embedded Human Kidney tissue.
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q92878
"
