Product Description
PSIP1 polyclonal antibody is available at gentaur for next week delivery
Background: The lens epithelium-derived growth factor (LEDGF), also designated p75p52, is a transcriptional coactivator that complexes with the human immunodeficiency virus type 1 (HIV-1) integrase. LEDGF/p75p52 is essential for the nuclear localization and chromosomal association of viral proteins. As the primary integrase-to-chromatin tethering factor for HIV-1, LEDGF/p75p52 is responsible for the cellular trafficking of lentiviral integrases. During apoptosis, LEDGF/p75p52 is cleaved at three sites by caspase-3 and caspase-7, contributing to the pathogenesis of atopic disorders.
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: PSIP1 polyclonal antibody detects endogenous levels of PSIP1 protein.
W4BiowMW: Refer to figures
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant protein of human PSIP1.Alternative Name:
p52; p75; PAIP; DFS70; LEDGF; PSIP2;Western blot analysis: Immunohistochemistry of paraffin-embedded rat testis using PSIP1 antibody.
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: O75475
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