Product Description
PSG1 polyclonal antibody is available at gentaur for next week delivery
Background: Pregnancy specific glycoprotein 1 (PSG1), also designated CD66f, is a member of the PSG family, a group of closely related secreted glycoproteins that are highly expressed in fetal placental syncytiotrophoblast cells. The members of the PSG protein family all have a characteristic N-terminal domain that is homologous to the immunoglobulin variable region. PSGs become detectable in serum during the first two to three weeks of pregnancy and increase as the pregnancy progresses, eventually representing the most abundant fetal protein in the maternal blood at term. PSGs function to stimulate secretion of TH2-type cytokines from monocytes, and they may also modulate the maternal immune system during pregnancy, thereby protecting the semi-allotypic fetus from rejection. PSGs are commonly expressed in trophoblast tumors. 11 human PSG proteins (PSG1-PSG11) have been described.
Applications: WB IHC IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 180-419 of human PSG1
W4BiowMW: ~ 55-72 kDa
Reactivity: Human
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 180-419 of human PSG1Alternative Name:
Pregnancy-specific beta-1-glycoprotein 1; PS-beta-G-1; PSBG-1; Pregnancy-specific glycoprotein 1; CD66 antigen-like family member F; Fetal liver non-specific cross-reactive antigen 1/2; FL-NCA-1/2; PSG95; Pregnancy-specific beta-1 glycoprotein C/D; PS-beta-C/D; CD66f; PSG1; B1G1; PSBG1; PSGGAWestern blot analysis: Western blot analysis of extracts of various cell lines, using PSG1 antibody at 1:1000 dilution. Lysates/proteins: 40ug per lane. Exposure time: 90s.
Immunohistochemistry: Immunohistochemistry of paraffin-embedded human colon carcinoma using PSG1 antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis: Immunohistochemistry of paraffin-embedded human stomach using PSG1 antibody at dilution of 1:100 (40x lens).
Host: Rabbit
Swiss-Prot: P11464
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