Product Description
PRPH polyclonal antibody is available at gentaur for next week delivery
Background: Peripherin is a type III intermediate filament protein that is expressed in peripheral and some central nervous system (CNS) neurons. Peripherin activation is known to be induced by leukemia inhibitory factor (LIF). LIF activates Peripherin by inducing members of STAT transcription factor family to bind to a specific promoter element in the Peripherin gene. IL-6 is also known to induce Peripherin expression. Although it is not essential for neurite formation, peripherin is necessary for cellular intermediate filament network formation. Peripherin, unlike most intermediate filament proteins, has been reported to be modified by tyrosine phosphorylation
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: PRPH polyclonal antibody detects endogenous levels of PRPH protein.
W4BiowMW: 54-62kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant protein of human PRPHAlternative Name:
Peripherin; Neurofilament 4; PRPH; NEF4; PRPH1Western blot analysis: Western blot analysis of extracts of various cell lines, using PRPH antibody at 1:1000 dilution.
Immunohistochemistry: Immunohistochemistry of paraffin-embedded rat heart using PRPH antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P41219
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