Product Description
PPA1 polyclonal antibody is available at gentaur for next week delivery
Background: PPA1 (Pyrophosphate phospho-hydrolase 1), also known as IOPPP (inorganic pyrophosphatase), PP1, PP or PPase, belongs to the PPase family of inorganic pyrophosphatases. Inorganic pyrophosphatases catalyze the intracellular conversion of pyrophosphate to inorganic phosphate, a key reaction for phosphate metabolism in cells. PPA1 is a ubiquitously expressed protein that localizes to the cytoplasm and is required for cell growth. It exists as a homodimer exhibiting magnesium dependent activity. The binding of two magnesium ions is required to stimulate PPA1 activity; however, both subunits in the homodimer are capable of binding four magnesium ions. The additional ions are useful in forming complexes with substrates and products. In addition, the activity of PPA1 can be inhibited by calcium.
Applications: WB
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: PPA1 polyclonal antibody detects endogenous levels of PPA1 protein.
W4BiowMW: ~ 37 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human PPA1.Alternative Name:
Inorganic pyrophosphatase; IOPPP; IPYR; PPA1; PPase; Pyp; Pyrophosphate phospho hydrolase; Pyrophosphate phospho-hydrolase;Western blot analysis: Western blot analysis of PPA1 polyclonal antibody
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q15181
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