Product Description
POU6F1 polyclonal antibody is available at gentaur for next week delivery
Background: Brn-5 (Brain-5), also known as POU6F1, MPOU or TCFB1, is a widely expressed protein but during embryogenesis is exclusively found in the developing brain and spinal cord. As is characteristic of Brn family members, Brn-5 contains two DNA-binding domains, namely the POU-specific domain and the POU homeodomain, which each contain an HTH (helix-turn-helix) motif. Brn-5 binds to CRH (corticotrophin-releasing hormone) elements with high affinity and is capable of both enhancing Prolactin gene expression and activating Pit-1 expression.
Applications: WB IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: POU6F1 polyclonal antibody detects endogenous levels of POU6F1 protein.
W4BiowMW: ~ 45 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human POU6F1.Alternative Name:
POU domain, class 6, transcription factor 1; Brain-specific homeobox/POU domain protein 5; Brain-5; Brn-5; mPOU homeobox protein; POU6F1; BRN5, MPOU, TCFB1Western blot analysis: Western blot analysis of extracts of various cell lines, using POU6F1 antibody.
Immunohistochemistry: Immunofluorescence analysis of MCF-7 cells using POU6F1 antibody.
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q14863
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