Product Description
PON2 polyclonal antibody is available at gentaur for next week delivery
Background: Paroxon is an organophosphorus anticholinesterase compound, used topically in the treatment of glaucoma. It is produced in vivo in mammals by microsomal oxidation of the insecticide parathion. Parathion is inert until transformed to paroxon. Paroxonase (paraoxonase or PON) is an arylesterase that is capable of hydrolyzing paroxon to produce p-nitrophenol. PONs are nonspecific and their classification is based not only on substrate specificity but also on tissue distribution, inhibition properties, and physicochemical characteristics such as electrophoretic mobility and molecular weight. In contrast to PON1, which is expressed mainly in the liver, PON2 is expressed in a variety of mouse tissues, including the pancreas. PON3 is associated with the high density lipoprotein fraction of serum. The genes which encode PON1-3 are physically linked and map to human chromosome 7q21.3.
Applications: WB IHC IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: PON2 polyclonal antibody detects endogenous levels of PON2 protein.
W4BiowMW: Refer to figures
Reactivity: Human,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human PON2.Alternative Name:
A esterase 2; A-esterase 2; Aromatic esterase 2; Paraoxonase 2; PON 2; PON2; PON2; Serum aryldialkylphosphatase 2; Serum paraoxonase/arylesterase 2;Western blot analysis:
Immunohistochemistry: Immunohistochemistry (IHC) analysis of PON2 polyclonal antibody in paraffin-embedded Human Kidney tissue.
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q15165
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