Product Description
POMGNT1 polyclonal antibody is available at gentaur for next week delivery
Background: The product of the POMGNT1 gene, protein O-mannose beta-1,2-N-acetylglucosaminyltransferase, participates in O-mannosyl glycan synthesis. POMGnT1 is an N(in)/C(out) (type II) membrane protein localized in the medial-Golgi that initiates the conversion of high mannose N-glycans to complex N-glycans. Specifically, POMGnT1 is a glycosylation enzyme that participates in the synthesis of O-mannosyl glycan, a laminin-binding ligand of alpha-dystroglycan that is rarely synthesized in mammals. Mutations in the POMGNT1 gene cause muscle-eye-brain disease (MEB), an autosomal recessive disorder characterized by congenital muscular dystrophy, ocular abnormalities and lissencephaly.
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: POMGNT1 polyclonal antibody detects endogenous levels of POMGNT1 protein.
W4BiowMW: ~ 90 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant protein of human POMGNT1.Alternative Name:
OMGnT1; GnT I.2; MGAT1.2; UNQ746/PRO1475Western blot analysis: Western blot analysis of extracts of various cells, using POMGNT1 antibody.
Immunohistochemistry: Immunohistochemistry of paraffin-embedded human prostate using POMGNT1 antibody at dilution of 1:100 (x40 lens).
Immunofluorescence analysis: Immunohistochemistry of paraffin-embedded human liver injury using POMGNT1 antibody at dilution of 1:100 (x40 lens).
Host: Rabbit
Swiss-Prot: Q8WZA1
"
