PMAIP1 polyclonal antibody

Product Description

PMAIP1 polyclonal antibody is available at gentaur for next week delivery

Background: Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1. Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.

Applications:  WB

Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability:  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity:  PMAIP1 polyclonal antibody detects endogenous levels of PMAIP1 protein.

W4BiowMW:  14 kDa

Reactivity: Human

Note:  For research use only, not for use in diagnostic procedure.

Immunogen:

Alternative Name:

Western blot analysis:  Western blot analysis of extracts of various cell lines, using PMAIP1 antibody at 1:1000 dilution.

Immunohistochemistry:

Immunofluorescence analysis:

Host:  Rabbit