Phospholamban (PLB) is a 52 amino acid phosphoprotein which regulates the calcium pump of cardiac sarcoplasmic reticulum (SR). PLB is an oligomer of five identical subunits each having a cytoplasmic and transmembrane domain. The cytoplasmic domain (residues 1 to 25) contains the phosphorylation sites and is highly basic and readily cleaved by proteases; whereas the transmembrane domain (residues 25 to 52) is mostly hydrophobic, protease resistant and stabilizes the pentamer.
Company name:
Abbexa
Product type:
Antibody
Product name:
PLB (pt17) Antibody
Catalog:
Abx032077
Quantity:
5 µl
Clonality:
Polyclonal
Host:
Domestic rabbit
Conjugate:
Nonconjugated
Reactivity:
Human