Product Description
PKC ε/ PRKCE polyclonal antibody is available at gentaur for next week delivery
Background: Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into many different isoforms (α, βI, βII, γ, ∂, é, Ω, h, †, λ/î, µ and n). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of PKC ∂ and é are independent of Ca++. On the other hand, most of the other PKC members possess phorbol ester-binding activities and kinase activities.
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: PRKCE polyclonal antibody detects endogenous levels of PRKCE protein.
W4BiowMW: ~ 100 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human PKC ε.Alternative Name:
Protein kinase C epsilon type; nPKC-epsilon; PRKCE; PKCEWestern blot analysis: Western blot analysis of extracts of various cell lines, using PKC ε antibody.
Immunohistochemistry: Immunohistochemistry (IHC) analysis of PKC ε polyclonal antibody in paraffin-embedded Human Colon tissue.
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q02156
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