Product Description
PER1 polyclonal antibody is available at gentaur for next week delivery
Background: This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers. Alternative splicing has been observed in this gene; however, these variants have not been fully described.
Applications: WB IHC IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: PER1 polyclonal antibody detects endogenous levels of PER1 protein.
W4BiowMW: ~ 160 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant protein of human PER1.Alternative Name:
PER; hPER; RIGUI;Western blot analysis: Immunohistochemistry of paraffin-embedded human gastric using PER1 antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry: Immunohistochemistry of paraffin-embedded rat kidney using PER1 antibody at dilution of 1:100 (x40 lens).
Immunofluorescence analysis: Immunohistochemistry of paraffin-embedded mouse stomach using PER1 antibody at dilution of 1:100 (x40 lens).
Host: Rabbit
Swiss-Prot: O15534
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