Product Description
PDGFR-α (phospho-Y1018) polyclonal antibody is available at gentaur for next week delivery
Background: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
Applications: WB
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: PDGFR-α (phospho-Y1018) polyclonal antibody detects endogenous levels of PDGFR-α protein only when phosphorylated at Tyr1018.
W4BiowMW: ~ 200 kDa
Reactivity: Human
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
A phospho specific peptide corresponding to residues surrounding Y1018 of human PDGFRA.Alternative Name:
CD140A; PDGFR2; PDGFR-2; RHEPDGFRA;Western blot analysis: Western blot analysis of extracts of HepG2 cell line, using Phospho-PDGFRA-Y1018 antibody.
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P16234
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