Product Description
PDCD6 polyclonal antibody is available at gentaur for next week delivery
Background: An increased intracellular Ca2+ concentration induces apoptotic cell death. Transiently elevated Ca2+ concentrations are required for glucocorticoid-mediated and T cell receptor-mediated pathways, leading to T cell apoptosis. ALG-2 (for apoptosis-linked gene 2) is a Ca2+ -binding protein that participates in regulatory events occuring late in the apoptotic program and where several death signals converge. ALG-2 is a protein expressed in normal brain, and to a greater extent in ischemic brain. The ALG-2 protein contains five EF-hand-like motifs and shares homology with members of the penta EF-hand family, which includes Calpain small subunits sorcin and Grancalcin.
Applications: WB IHC IF IP
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: PDCD6 polyclonal antibody detects endogenous levels of PDCD6 protein.
W4BiowMW: ~ 16 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human PDCD6.Alternative Name:
Programmed cell death protein 6; Apoptosis-linked gene 2 protein; Probable calcium-binding protein ALG-2; PDCD6; ALG2Western blot analysis: Western blot analysis of extracts of various cells, using PDCD6 antibody.
Immunohistochemistry: Immunohistochemistry of paraffin-embedded rat kidney using PDCD6 antibody at dilution of 1:200 (40x lens).
Immunofluorescence analysis: Immunoprecipitation analysis of 200ug extracts of HepG2 cells, using 3 ug PDCD6 antibody.
Host: Rabbit
Swiss-Prot: O75340
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