Product Description
PCSK9 polyclonal antibody is available at gentaur for next week delivery
Background: This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing results in multiple transcript variants.
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: PCSK9 polyclonal antibody detects endogenous levels of PCSK9 protein.
W4BiowMW: 60, 72kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
A synthetic peptide of human PCSK9Alternative Name:
FH3; HCHOLA3; LDLCQ1; NARC-1; NARC1; PC9Western blot analysis: Western blot analysis of extracts of various cell lines, using PCSK9 Antibody at 1:1000 dilution.
Immunohistochemistry: Immunohistochemistry of paraffin-embedded rat kidney tissue using PCSK9 antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q8NBP7
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