Product Description
PARP polyclonal antibody is available at gentaur for next week delivery
Background: PARP, a 116 kDa nuclear poly (ADP-ribose) polymerase, appears to be involved in DNA repair in response to environmental stress. This protein can be cleaved by many ICE-like caspases in vitro and is one of the main cleavage targets of caspase-3 in vivo. In human PARP, the cleavage occurs between Asp214 and Gly215, which separates the PARP amino-terminal DNA binding domain (24 kDa) from the carboxy-terminal catalytic domain (89 kDa).
Applications: WB IHC IF IP CHIP
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: PARP polyclonal antibody detects endogenous levels of PARP protein.
W4BiowMW: ~ 100, 110 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human PARP.Alternative Name:
Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1; PARP1; ADPRT; PPOLWestern blot analysis: Western blot analysis of extracts of [KO Validated] PARP1 antibody.
Immunohistochemistry: Immunohistochemistry of paraffin-embedded human breast cancer using PARP1 Antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis: Immunofluorescence - [KO Validated] PARP1 Rabbit pAb
Host: Rabbit
Swiss-Prot: P09874
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