Product Description
NRG1 polyclonal antibody is available at gentaur for next week delivery
Background: Neuregulin-1 gene, NRG1, encodes numerous splice variants with differing transcription initiation sites. Neuregulin-1 includes a range of isoforms with varying glycosylation, regulation of expression and function. Neuregulin-1 splice variants each bear an EGF-like domain, though otherwise have unique domain structures, differing functions and discrete tissue distribution. Six types of Neuregulin-1 isoform groups have been defined based on their structural features. Three types are most often described, type I (ARIA, NDF or HRG), type II (GGF) and type III (SMDF). Neuregulin-1 has been linked to schizophrenia and has diverse neural functions. Neuregulin-1 affects cell migration, the differentiation of neural crest and Schwann cells, and acts to upregulate the expression of acetylcholine receptors at muscle fibers during the formation of neuromuscular junctions.
Applications: WB IHC IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: NRG1 polyclonal antibody detects endogenous levels of NRG1 protein.
W4BiowMW: ~ 70 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human NRG1.Alternative Name:
Acetylcholine receptor inducing activity; Acetylcholine receptor-inducing activity; ARIA; Breast cancer cell differentiation factor p45; ERBB2 p185 activator; GGF 2; GGF; GGF2; Glial growth factor; Heregulin alpha; Heregulin; heregulin; alpha (45; ERBB2 p185-activator); HGL; HRG 1; HRG; HRG1; HRGA; MST131; NDF; Neu differentiation factor; Neuregulin 1; neuregulin 1 type IV beta 1a; neuregulin 1 type IV beta 3; Neuregulin-1; Neuregulin1; NRG 1; nrg1; NRG1; OTTHUWestern blot analysis: WesternBlot (WB) analysis of NRG1 polyclonal antibody.
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q02297
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