Product Description
NFkB-p100 polyclonal antibody is available at gentaur for next week delivery
Background: This gene encodes one of the subunits of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB transcription factor complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The NFkB complex can consist of different subunits that form both homo- or heterodimers which bind specific kappa-B elements in target genes. This gene encodes the p100 subunit that is processed into the active p52 subunit. This protein can function as both a transcriptional activator and repressor, depending on its dimer partner. Alternate splicing results in both coding and non-coding variants.
Applications: WB IHC IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: NFkB-p100 polyclonal antibody detects endogenous levels of NFkB-p100 protein.
W4BiowMW: ~ 110 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
A synthetic peptide of human NFKB2.Alternative Name:
p52; p105; H2TF1; LYT10; LYT-10; NF-kB2;Western blot analysis: Western blot analysis of extracts of various cell lines, using NFKB2 antibody.
Immunohistochemistry: Immunohistochemistry of paraffin-embedded rat liver using NFKB2 antibody at dilution of 1:200 (400x lens).
Immunofluorescence analysis: Immunohistochemistry of paraffin-embedded rat testis using NFKB2 antibody at dilution of 1:200 (400x lens).
Host: Rabbit
Swiss-Prot: Q00653
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