Product Description
NCAM1 polyclonal antibody is available at gentaur for next week delivery
Background: NCAM (neural cell adhesion molecule, CD56) is an adhesion glycoprotein with five extracellular immunoglobulin-like domains followed by two fibronectin type III repeats. Structural diversity is introduced by alternative splicing resulting in different cytoplasmic domains . NCAM mediates neuronal attachment, neurite extension and cell-cell interactions through homo and heterophilic interactions. PSA (polysialic acid) post-translationally modifies NCAM and increases the metastatic potential of small cell lung carcinoma, Wilms+ tumor, neuroblastoma and rhabdomyosarcoma . CD56 and CD16 are commonly used to identify NK cells although some cells with the T cell markers CD3 and CD4 also express CD56 .
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: NCAM1 polyclonal antibody detects endogenous levels of NCAM1 protein.
W4BiowMW: ~ 160 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant protein of human NCAM1.Alternative Name:
CD56; NCAM; MSK39;Western blot analysis: Western blot analysis of extracts of various cell lines, using NCAM1 antibody.
Immunohistochemistry: Immunohistochemistry of paraffin-embedded human stomach using NCAM1 antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P13591
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