Product Description
MMP-8 polyclonal antibody is available at gentaur for next week delivery
Background: The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-8 (also designated neutrophil collagenase, PMNL collagenase or collagenase-2) degrades fibrillar collagen types I, II and III. Unlike other members of the MMP family, MMP-8 is expressed exclusively in inflammatory conditions. MMP-8 is highly expressed in the postpartum uterus, and it is thought to be involved in the postpartum involution of the uterus. MMP-8 is also the predominant collagenase expressed in ulcers and healing wounds.
Applications: WB IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: MMP-8 polyclonal antibody detects endogenous levels of MMP-8 protein.
W4BiowMW: ~ 65 kDa
Reactivity: Human,Mouse
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human MMP-8.Alternative Name:
Neutrophil collagenase; Matrix metalloproteinase-8; MMP-8; PMNL collagenase; PMNL-CL; MMP8; CLG1Western blot analysis: Western blot analysis of MMP-8 polyclonal antibody
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P22894
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