Product Description
MLPH polyclonal antibody is available at gentaur for next week delivery
Background: Slac2-a (for synaptotagmin-like protein (Slp) homolog lacking C2 domains-a) links Rab27A on melanosomes with Myosin VA in melanocytes. Slac2-a binds Myosin VA through a C-terminal region and GTP-bound Rab27A through its synaptotagmin-like protein homology domain (SHD), which is located near the N-terminus. The transport of pigment and cytotoxic granules in melanocytes requires the stable formation of this complex, and thus mutations in the binding domains of the three protein components may cause albinism and/or severe immune disorders.
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: MLPH polyclonal antibody detects endogenous levels of MLPH protein.
W4BiowMW: ~ 75 kDa
Reactivity: Human
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human MLPH.Alternative Name:
Melanophilin; Exophilin-3; Slp homolog lacking C2 domains a; SlaC2-a; Synaptotagmin-like protein 2a; MLPH; SLAC2AWestern blot analysis: Western blot analysis of extracts of various cell lines, using MLPH antibody at 1:1000 dilution.
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q9BV36
"
