Product Description
MKK3 (Phospho-T222) polyclonal antibody is available at gentaur for next week delivery
Background: The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinaseegulatory threonine and tyrosine residues present in thehr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK5, whereas MEK-6hosphorylates p38 and p38b. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.
Applications: WB IHC IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: MKK3 (Phospho-T222) polyclonal antibody detects endogenous levels of MKK3 protein only when phosphorylated at Thr222.
W4BiowMW: ~ 40 kDa
Reactivity: Human,Mouse,Zebrafish
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic phosphopeptide derived from human MKK3 around the phosphorylation site of Threonine 222.Alternative Name:
Dual specificity mitogen-activated protein kinase kinase 3; MAP kinase kinase 3; MAPKK 3; MAPK/ERK kinase 3; MEK 3; Stress-activated protein kinase kinase 2; SAPK kinase 2; SAPKK-2; SAPKK2; MAP2K3; MEK3; MKK3; PRKMK3; SKK2Western blot analysis: Western blot (WB) analysis of MKK3 (Phospho-T222) polyclonal antibody at 1:500 dilution LaneA:Zebrafish
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P46734
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