Product Description
MGLL polyclonal antibody is available at gentaur for next week delivery
Background: Monoglyceride Lipase (MGL), also known as Lysophospholipase-like or Lysophospholipase homolog, is a ubiquitously expressed protein that functions in the endocannabinoid system. It is required for the the degradation of endocannabinoids and the complete hydrolysis of monoglycerides. In addition, Monoglyceride Lipase functions together with HSL (hormone-sensitive lipase) to hydrolyze intracellular triglyceride to glycerol and fatty acids. Monoglyceride Lipase is a presynaptic, cytosolic enzyme that functions as a serine hydrolase and specifically hydrolyzes 2- and 1(3)-ester bonds of monoglycerides. In particular, Monoglyceride Lipase is responsible for the inactivation and degradation of 2-arachidonoylglycerol (2-AG). 2-AG is a monoglyceride produced by neurons that activates cannabinoid receptors and possibly modulates neurotransmitter release and synaptic plasticity.
Applications: WB
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: MGLL polyclonal antibody detects endogenous levels of MGLL protein.
W4BiowMW: ~ 60 kDa
Reactivity: Human,Mouse
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human MGLL.Alternative Name:
Monoglyceride lipase; MGL; HU-K5; Lysophospholipase homolog; Lysophospholipase-like; Monoacylglycerol lipase; MAGL; MGLLWestern blot analysis: WesternBlot (WB) analysis of MGLL polyclonal antibody
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q99685
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