Product Description
MCM7 polyclonal antibody is available at gentaur for next week delivery
Background: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage
Applications: WB IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: MCM7 polyclonal antibody detects endogenous levels of MCM7 protein.
W4BiowMW: ~ 91 kDa
Reactivity: Human,Mouse
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human MCM7.Alternative Name:
DNA replication licensing factor MCM7; CDC47 homolog; P1.1-MCM3; MCM7; CDC47; MCM2Western blot analysis: WesternBlot (WB) analysis of MCM7 polyclonal antibody
Immunohistochemistry:
Immunofluorescence analysis: Immunofluorescence analysis of Hela cells, using MCM7 polyclonal antibody
Host: Rabbit
Swiss-Prot: P33993
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