Product Description
MCM3 polyclonal antibody is available at gentaur for next week delivery
Background: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation.
Applications: WB IHC IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: MCM3 polyclonal antibody detects endogenous levels of MCM3 protein.
W4BiowMW: ~ 105 kDa
Reactivity: Human,Mouse,Rat,Monkey
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human MCM3.Alternative Name:
Cervical cancer proto oncogene 5; DNA polymerase alpha holoenzyme associated P1; DNA polymerase alpha holoenzyme associated protein P1; DNA polymerase alpha holoenzyme-associated protein P1; DNA replication factor MCM3; DNA replication licensing factor MCM3; HCC 5; HCC5; hRlf beta subunit; Human cervical cancer proto oncogene 5; MCM 3; mcm3; MCM3 minichromosome maintenance deficient 3; MCM3; MGC1157; Minichromosome maintenance complex component 3; Minichromosome maintenanceWestern blot analysis: WesternBlot (WB) analysis of MCM3 polyclonal antibody
Immunohistochemistry: Immunohistochemistry (IHC) analysis of MCM3 polyclonal antibody in paraffin-embedded Human Esophageal Cancer tissue.
Immunofluorescence analysis: Immunofluorescence analysis of Hela cells, using MCM3 polyclonal antibody
Host: Rabbit
Swiss-Prot: P25205
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