MB67 polyclonal antibody

Product Description

MB67 polyclonal antibody is available at gentaur for next week delivery

Background: This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists.

Applications:  WB IF

Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability:  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity:  MB67 polyclonal antibody detects endogenous levels of MB67 protein.

W4BiowMW:  ~ 45 kDa

Reactivity: Human,Mouse,Rat

Note:  For research use only, not for use in diagnostic procedure.

Immunogen:

Recombinant full length Human MB67.

Alternative Name:

Nuclear receptor subfamily 1 group I member 3; Constitutive activator of retinoid response; Constitutive active response; Constitutive androstane receptor; CAR; Orphan nuclear receptor MB67; NR1I3; CAR

Western blot analysis:  Western blot analysis of MB67 polyclonal antibody

Immunohistochemistry:

Immunofluorescence analysis: Immunofluorescence analysis of U2OS cells, using MB67 polyclonal antibody

Host:  Rabbit

Swiss-Prot: Q14994

 

 

 

 

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