Product Description
MARS polyclonal antibody is available at gentaur for next week delivery
Background: MARS2 (methionyl-tRNA synthetase 2, mitochondrial), also known as MetRS or MtMetRS, is a 593 amino acid mitochondrial matrix protein that belongs to the class-I aminoacyl-tRNA synthetase family. MARS2 functions at an optimal pH of 7.8 to 8.2 and contains HIGH and KMSKS motifs, both of which are signature sequences found in all class I synthetases. The gene encoding MARS2 maps to human chromosome 2q33.1. Consisting of of 237 million bases and encoding over 1,400 genes, chromosome 2 is the second largest human chromosome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8.
Applications: WB
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: MARS polyclonal antibody detects endogenous levels of MARS protein.
W4BiowMW: ~ 110 kDa
Reactivity: Human
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant protein of human MARS.Alternative Name:
Methionyl-tRNA synthetase; MetRSWestern blot analysis: Western blot analysis of extracts of various cells, using MARS antibody.
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P56192
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