Product Description
MAPKBP1 polyclonal antibody is available at gentaur for next week delivery
Background: MAP kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. MAPKBP-1 (mitogen-activated protein kinase binding protein 1), also known as JNKBP-1, is a 1,514 amino acid protein that contains twelve WD repeats. Induced by TRAF2 (TNF receptor-associated factor 2) and Tak1 (TGF-β-activated kinase 1), MAPKBP-1 is thought to act an adaptor protein for NFκB (nuclear factor κ-B) activation. MAPKBP-1 interacts with JNK3 and may promote TRAF2 polyubiquitination. MAPKBP-1 exists as six alternatively spliced variants and is encoded by a gene located on human chromosome 15. Human chromosome 15 houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: MAPKBP1 polyclonal antibody detects endogenous levels of MAPKBP1 protein.
W4BiowMW: ~ 164 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
A synthetic peptide of human MAPKBP1.Alternative Name:
Mitogen-activated protein kinase-binding protein 1; JNK-binding protein 1; JNKBP-1; JNKBP1; KIAA0596Western blot analysis: Western blot analysis of MAPKBP1 antibody.
Immunohistochemistry: Immunohistochemistry of paraffin-embedded mouse stomach using MAPKBP1 antibody at dilution of 1:100 (x40 lens).
Immunofluorescence analysis: Immunohistochemistry of paraffin-embedded human stomach using MAPKBP1 antibody at dilution of 1:100 (x40 lens).
Host: Rabbit
Swiss-Prot: O60336
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