Product Description
MAD1L1 polyclonal antibody is available at gentaur for next week delivery
Background: Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. May recruit MAD2L1 to unattached kinetochores. Has a role in the correct positioning of the septum. Required for anchoring MAD2L1 to the nuclear periphery. Binds to the TERT promoter and represses telomerase expression, possibly by interfering with MYC binding.
Applications: WB IHC IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: MAD1L1 polyclonal antibody detects endogenous levels of MAD1L1 protein.
W4BiowMW: ~ 95 kDa
Reactivity: Human,Mouse
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human MAD1L1.Alternative Name:
Mitotic spindle assembly checkpoint protein MAD1; Mitotic arrest deficient 1-like protein 1; MAD1-like protein 1; Mitotic checkpoint MAD1 protein homolog; HsMAD1; hMAD1; Tax-binding protein 181; MAD1L1; MAD1; TXBP181Western blot analysis: WesternBlot (WB) analysis of MAD1L1 polyclonal antibody
Immunohistochemistry: Immunohistochemistry (IHC) analysis of MAD1L1 polyclonal antibody in paraffin-embedded Human Lung Cancer tissue.
Immunofluorescence analysis: Immunofluorescence analysis of Hela cells, using MAD1L1 polyclonal antibody
Host: Rabbit
Swiss-Prot: Q9Y6D9
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