Product Description
LPHN2 polyclonal antibody is available at gentaur for next week delivery
Background: The Latrophilin family of G protein-coupled receptors consists of three members, latrophilin-1, 2 and 3, each of which displays distinct tissue distribution and function. Latrophilin-1, the most characterized member of this family, acts as a receptor for a-latrotoxin, a component of venom from the black widow spider. Binding of a-latrotoxin to latrophilin-1 triggers synaptic vesicle exocytosis via both Ca2+-dependent and -independent mechanisms, resulting in vesicle depletion. Latrophilin-1 is abundant in brain and present in endocrine cells. Latrophilin-3 is also brain-specific, whereas latrophilin-2 expression is ubiquitous.
Applications: WB
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: LPHN2 polyclonal antibody detects endogenous levels of LPHN2 protein.
W4BiowMW: ~ 220 kDa
Reactivity: Human
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
A synthetic peptide corresponding to residues in Human LPHN2Alternative Name:
Latrophilin-2; Calcium-independent alpha-latrotoxin receptor 2; CIRL-2; Latrophilin homolog 1; Lectomedin-1; LPHN2; KIAA0786; LEC1; LPHH1Western blot analysis: Western blot (WB) analysis of LPHN2 pAb at 1:500 dilution Lane1:U-87MG whole cell lysate(40ug) Lane2:H1792 whole cell lysate(40ug) Lane3:HepG2 whole cell lysate(40ug)
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: O95490
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